Doctor Fungus - Mycoses in Patients Receiving Tumor Necrosis Factor-α Inhibitor

John W. Baddley, MD, MSPH Introduction The number of patients receiving immunosuppressive agents has increased over the past decade and is expected to increase substantially in the near future. Therapeutic antibodies have become an important class of drugs, with annual sales that exceeded $27 billion in 2007[(A):1].  Important new therapeutic biologics include the TNF-a inhibitors (TNFi) infliximab, etanercept, adalimumab, certolizumab pegol and golimumab. These drugs are approved for the treatment of one or more of a number of diseases including rheumatoid arthritis, psoriatic arthritis, plaque psoriasis, Crohn’s disease, juvenile idiopathic arthritis and ankylosing spondylitis.  Although these drugs have revolutionized the […]