Epidemiological Characteristics and Outcome of Viral Respiratory Tract Infections in the First Year After Allogeneic Hematopoietic Cell Transplantation
Resource type
Journal Article
Authors/contributors
- Van Praet, Jens T (Author)
- Huysman, Andreas (Author)
- De Knijf, Eline (Author)
- De Buyser, Stefanie (Author)
- Snauwaert, Sylvia (Author)
- Van Droogenbroeck, Jan (Author)
- Lodewyck, Tom (Author)
- Schauwvlieghe, Alexander (Author)
- Selleslag, Dominik (Author)
- Reynders, Marijke (Author)
Title
Epidemiological Characteristics and Outcome of Viral Respiratory Tract Infections in the First Year After Allogeneic Hematopoietic Cell Transplantation
Abstract
Abstract
Adverse outcomes of viral respiratory tract infections (RTIs) have been reported in recipients of allogeneic hematopoietic cell transplantation. Using a laboratory-developed multiparameter polymerase chain reaction in a consecutive series of 242 patients, we found the highest incidence of viral RTI in the preengraftment phase. The occurrence of multiple episodes of viral RTI or viral pneumonia was significantly associated with a higher hazard of nonrelapse mortality in the first year after transplantation. We observed a 90-day mortality of 19.7% after viral RTI, which was significantly different between patient groups stratified according to the immunodeficiency scoring index.
Publication
The Journal of Infectious Diseases
Pages
jiae108
Date
2024-03-01
Language
en
ISSN
0022-1899, 1537-6613
Accessed
4/27/24, 1:09 PM
Library Catalog
DOI.org (Crossref)
Citation
Van Praet, J. T., Huysman, A., De Knijf, E., De Buyser, S., Snauwaert, S., Van Droogenbroeck, J., Lodewyck, T., Schauwvlieghe, A., Selleslag, D., & Reynders, M. (2024). Epidemiological Characteristics and Outcome of Viral Respiratory Tract Infections in the First Year After Allogeneic Hematopoietic Cell Transplantation. The Journal of Infectious Diseases, jiae108. https://doi.org/10.1093/infdis/jiae108
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