Emerging Role of Plasma Microbial Cell-free DNA in the Diagnosis of Pediatric Mucormycosis
Resource type
Journal Article
Authors/contributors
- Gracia, Michael (Author)
- Hadley, Emma (Author)
- Ramchandar, Nanda (Author)
- Coufal, Nicole G. (Author)
Title
Emerging Role of Plasma Microbial Cell-free DNA in the Diagnosis of Pediatric Mucormycosis
Abstract
Mucormycosis is a rare and devastating angioinvasive infection that can be challenging to diagnose due to the low sensitivity of current noninvasive diagnostics and the lack of a “gold standard” reference test. We describe a retrospective case series of children with suspected mucormycosis where plasma microbial cell-free DNA testing was utilized in the diagnostic evaluation to illustrate the ways in which microbial cell-free DNA testing can noninvasively contribute to the evaluation and management of at-risk, immunosuppressed patients suspected of mucormycosis.
Publication
Pediatric Infectious Disease Journal
Date
2024-03-18
Language
en
ISSN
0891-3668
Accessed
5/23/24, 8:28 PM
Library Catalog
DOI.org (Crossref)
Citation
Gracia, M., Hadley, E., Ramchandar, N., & Coufal, N. G. (2024). Emerging Role of Plasma Microbial Cell-free DNA in the Diagnosis of Pediatric Mucormycosis. Pediatric Infectious Disease Journal. https://doi.org/10.1097/INF.0000000000004331
ORGANISMS
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