Histoplasmosis beyond HIV: Clinical characteristics and outcomes in non-HIV population

Resource type
Journal Article
Title
Histoplasmosis beyond HIV: Clinical characteristics and outcomes in non-HIV population
Abstract
Histoplasmosis is an endemic and invasive mycosis caused by Histoplasma capsulatum. We conducted a retrospective study comparing non-HIV immunosuppressed patients with a historical cohort of HIV and histoplasmosis. We included 199 patients with proven or probable histoplasmosis, of which 25.1% were non-HIV. Diabetes mellitus, chronic kidney disease, hematologic neoplasms, rheumatologic diseases and transplants were more frequent among non-HIV patients (p<0.01). Death after diagnosis occurred in 44% patients. 44% of immunocompromised non-HIV patients died within the first 6-week period following their diagnosis. A high suspicion index for histoplasmosis should be kept in immunosuppressed patients.
Publication
Open Forum Infectious Diseases
Pages
ofae079
Date
2024-02-15
Journal Abbr
Open Forum Infectious Diseases
ISSN
2328-8957
Short Title
Histoplasmosis beyond HIV
Accessed
2/20/24, 8:13 AM
Library Catalog
Silverchair
Citation
Tello-Mercado, A. C., Martínez-Guerra, B., Román-Montes, C. M., Seoane-Hernandez, L., Rangel-Cordero, A., Martínez-Gamboa, R. A., Sifuentes-Osornio, J., Ponce-de-León, A., González Lara, M. F., & Niembro-Ortega, M. D. (2024). Histoplasmosis beyond HIV: Clinical characteristics and outcomes in non-HIV population. Open Forum Infectious Diseases, ofae079. https://doi.org/10.1093/ofid/ofae079
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