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Molecular Epidemiology, Natural History, and Long-Term Outcomes of Multidrug-Resistant Enterobacterales Colonization and Infections Among Solid Organ Transplant Recipients
Resource type
Journal Article
Authors/contributors
- Hong Nguyen, M (Author)
- Shields, Ryan K (Author)
- Chen, Liang (Author)
- William Pasculle, A (Author)
- Hao, Binghua (Author)
- Cheng, Shaoji (Author)
- Sun, Jonathan (Author)
- Kline, Ellen G (Author)
- Kreiswirth, Barry N (Author)
- Clancy, Cornelius J (Author)
Title
Molecular Epidemiology, Natural History, and Long-Term Outcomes of Multidrug-Resistant Enterobacterales Colonization and Infections Among Solid Organ Transplant Recipients
Abstract
Twenty-five percent of transplant recipients were gastrointestinally colonized by multidrug-resistant Enterobacterales, which predisposed to invasive infections. Infections were associated with low short-term and long-term mortality, but recurrences were common for years. Whole-genome phylogenetic analyses linked infections to colonizing strains.
Publication
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Date
2021-5-10
Volume
74
Issue
3
Pages
395-406
Journal Abbr
Clin Infect Dis
Accessed
2/12/23, 6:51 AM
ISSN
1058-4838
Library Catalog
PubMed Central
Extra
PMID: 33970222
PMCID: PMC8834656
Citation
Hong Nguyen, M., Shields, R. K., Chen, L., William Pasculle, A., Hao, B., Cheng, S., Sun, J., Kline, E. G., Kreiswirth, B. N., & Clancy, C. J. (2021). Molecular Epidemiology, Natural History, and Long-Term Outcomes of Multidrug-Resistant Enterobacterales Colonization and Infections Among Solid Organ Transplant Recipients. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 74(3), 395–406. https://doi.org/10.1093/cid/ciab427
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